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CODE: C140
INTRODUCTION:
DESCRIPTION
Follicular dysplasias are a group of syndromes which have in common abnormal hair loss and changes in coat quality.
Hair loss starts at an early age and progresses very slowly. The changes are consistent in the different breeds
affected, suggesting a genetic connection. Black Hair Follicular Dysplasia is a rare inherited disorder that is seen
in mixed-breed and purebred dogs. Hair loss occurs at a very early age in black areas on black or black and white
dogs. Large Munsterlanders occasionally carry the ff alleles for Black Hair Follicular Dysplasia.
This disorder results in these dogs that are gray and white instead of black and white. Hair in the gray areas is
very brittle and tends to break off within several weeks after it grows in, but hair in the white areas is normal.
INHERITANCE
Black Hair Follicular Dysplasia is inherited as an autosomal recessive trait; therefore two copies of the
f allele, one inherited from each parent, have to be present for a dog to be affected by the disease.
Carriers (dogs with one copy of the f allele and one copy of the F allele) are
clinically unaffected, but can pass the f allele onto their offspring.
DNA TEST
This DNA test provides reliable identification of dogs that carry the f allele. The DNA test
allows a breeder to control the f allele frequency in Large Munsterlander thus preventing the
production of puppies affected with Black Hair Follicular Dysplasia. This DNA test accurately and specifically
identifies normal, carriers (heterozygous) and affected dogs.
BREEDS:
Large Munsterlander
TEST RESULTS:
| Result |
Genotype |
Interpretation |
| Normal |
FF |
Homozygous for F allele, will never develop the disease |
| Carrier |
Ff |
Carries one F allele, but will never develop the disease |
| Affected |
ff |
Homozygous for F allele and will develop the disease |
SAMPLES:
Two types of samples can be submitted for this DNA test:
- A blood sample in a lavender (EDTA) tube;
- Cheek swabs - Order a Sample Collection Kit!
PRICE:
-$105.00 *
Special contract prices are available for Breeder Clubs. Please contact us for more information.
* - subject to the applicable taxes (5% GST Canadian Residents only)
CERTIFICATION OF RESULTS:
HealthGene will provide a certificate for each test result.
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